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In The Longevity Factor, noted neuroscientist and surgeon Joseph Maroon, M.D., offers the definitive look at recent scientific breakthroughs identifying a group of natural substances - including the much publicized molecule resveratrol - that can actually activate a specific set of genes in humans that promote a longer, healthier life. These substances, which make red wine, dark chocolate, and green tea good for us, appear to stave off a wide array of age-related diseases and keep us feeling young and vital. Resveratrol is the centerpiece of headline-making research being conducted at the Harvard Medical School and elsewhere. Only recently, however, have scientists discovered how to isolate resveratrol and concentrate it into an affordable and safe supplement. Already, more than 200 supplements featuring resveratrol have flooded the market, and there are countless more on the way. But which ones work best? What is a consumer to look for on the label? Since resveratrol is a natural substance, can you get enough of it through diet alone, or should you combine diet with a supplement? And what lies on the horizon from the pharmaceutical industry? All those questions and many more are answered in this immensely informative and practical book. Joseph Maroon offers the first-ever inside look at the amazing research that has led to the discovery of resveratrol and similar substances with the miraculous ability to activate our own longevity genes. He also offers his own diet plan and sound, reader-friendly advice for living a longer, healthier, and more balanced life with or without supplements. The Longevity Factor promises to be the authoritative source for everyone who wants to know more about how we can shift from the current paradigm of aging to a disease-free golden age of health, longevity and fitness. Pages: 352 Cover: Hard Publisher: Atria Books Date Published: 2009 Table of Contents: Foreward by Joseph A. Baur, PhD: ix Introduction: xi Part I: Discovery, Xenohormesis, and Xeno Factors 1. The Origins of Life: 3 2. Molecular Pioneers and the Discovery of Longevity Genes: 12 3. Causes of Aging: 20 4. Calorie Restriction and Longevity: 31 5. Beginning to Understand Longevity Genes: 37 6. The French Paradox and the Holy Grail of Aging: 47 Part II: The Australian Extract 7. Serendipity and the Australian Connection: 59 8. Leaps of Faith: 67 Part III: Health Benefits of Xeno Factors 9. Live Longer, Improve Memory, Enhance Endurance and More: 75 10. Diabetes: 85 11. Cardio Protection: 93 12. The Anticancer Effect: 106 13. Stroke Prevention: 117 14. Degenerative Brain Diseases and Brain Protection: 123 15. Other Inflammatory Conditions: 133 16. Sources, Safety, Bioavailability and Dosage: 141 17. The Hows and Whys of Overweight: 153 Part IV: Unlocking the Genetic Secrets to Living Healthier and Longer 18. What's a Person to Do?: 167 19. The Four-Step Xeno Longevity/Weight-Loss Program: 199 20. Summing Up: 269 Appendix A: Classification of Xeno Factors: 281 Appendix B: Timeline of Discovery: 284 Appendix C: Existing Patents and NIH-Funded Clinical Trials: 288 Appendix D: Partial List of Fish Oil Supplements and Multivitamins: 292 Acknowledgements: 293 References: 296 Index: 329 About the Author: Joseph Maroon, M.D., F.A.C.S., studied medicine at Indiana University, Georgetown and Oxford University. Dr. Maroon is a world-renowned neurosurgeon and former president of the Congress of Neurological Surgeons, the largest society of its kind in North America. He has been the team neurosurgeon for the Pittsburgh Steelers for the past twenty-five years and currently is a professor and Heindl Scholar in Neuroscience at the University of Pittsburgh Medical Center. A lifelong athlete, he has competed in more than fifty triathlons, including three Hawaiian Ironman Championship competitions. |
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