Product Description: Jarrow Formulas SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S form.
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid), SAM-e is a chiral molecule consisting of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-E is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits.
SAM-e supports the production of healthy connective tissue through transulfuration. In this process critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are components of the body's endogenous antioxidant network and important for liver function, including phase II detoxification.
Warnings: Individuals using prescribed medication such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use. Keep out of the reach of children.
Additional Info: Jarrow Formulas SAM-e is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken. Store in a cool, dry place. Suitable for vegetarians/vegans.
Packaging: Paper Box
Other Ingredients: Cellulose, Mannitol, Glycerol Behenate, Magnesium Stearate (Vegetable Source), Silicon Dioxide, Sodium Starch Glycolate, Enteric Coating (Methacrylate Copolymers, Magnesium Silicate, Triethyl Citrate, and Riboflavin)
Does Not Contain: Wheat, Gluten, Soybeans, Dairy, Egg, Fish/Shellfish, Peanuts/Tree Nuts.
Suggested Use: Take 1 tablet 1 to 2 times per day on an empty stomach, or as directed by your qualified healthcare professional.