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Three Brains for Overall Health
Submitted by Natural Factors®

When it comes to mental health, it's not all in your head! There is an intricate communication network between the heart, brain, and gut. According to Karen Jensen, naturopathic doctor and author of Three Brains, there is a growing body of evidence that suggests we actually have three "brains" and their interaction influences our overall health. She suggests, "nutrients from whole foods, exercise, and supplements are effective, noninvasive ways to support the 'three brains' interaction and optimize mental health and cognition."

Head Brain–Cognition, clarity of thought, and memory are key brain functions. Our brains have high oxygen and energy demands. As a result, when nutritional gaps, stress, or irregular sleep prevail, then mental sharpness and concentration can suffer.

Heart Brain–Recent discoveries in the area of neurocardiology have shown that the messages the heart sends the brain affect our perceptions, mental processes, feelings, and performance in profound ways.


Gut Brain–The gut brain contains approximately 100 million neurons and it can work both independently of, and in conjunction with, the head brain. Studies suggest gut microbiota communicate with the head brain and may play a role in mood and cognition. This gut-brain connection is an exciting emerging field called neurogastroenterology.

Natural Factors® Three Brains™ line of supplements is designed to support the critical relationship between the HEART BRAIN, the GUT BRAIN, and the HEAD BRAIN.

Support for Cognitive Health & Brain Function*
Higher Thoughts™ is a comprehensive blend of omega-3 fatty acids, including both eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and phospholipids, which all work together to support cognitive and cardiovascular health. Omega-3 fatty acids, phosphatidylserine (PS), phosphatidylcholine (PC), and L-alpha-glycerylphosphorylcholine (Alpha-GPC) normalize the brain's lipid content and support healthy neurotransmitter function.

PC is the major phospholipid in the body and a precursor to acetylcholine, an important brain chemical involved in both memory and thought. Alpha-GPC increases plasma levels of choline and, therefore, increases the production of acetylcholine and PC as well. Green tea extract promotes calm mental focus, stamina, and supports healthy blood vessels, while also acting as a powerful antioxidant to protect the brain from free radical damage. The brain and heart have high oxygen and energy demands. Frequent nutritional gaps, mental and physical stress, and irregular sleep patterns all contribute to reduced cognitive and/or cardiovascular function. Higher Thoughts™ helps ensure a steady flow of nutrients to both the brain and the heart.

Sleeplessness Due to Everyday Mental Stress*
The Best-Sleep™ combines five herbal extracts that have traditionally been used in herbal medicine to promote calmness and support healthy sleep. Passionflower extract (Passiflora incarnata), California poppy extract (Eschscholzia californica), skullcap extract (Scutellaria lateriflora), and linden extract (Tilia cordata) are all valued for their natural sedative affects that promote healthy sleep. Passionflower, California poppy, and skullcap all have relaxing affects and promote overall mental calmness. Passionflower also has analgesic properties, which may help ease physical pains that can inhibit or interrupt sleep. In addition to oxygen and good nutrition, our bodies require sufficient sleep in order to support healthy cognitive function, including healthy mood and coping with stress, as well as keeping the body's immune system strong. However, nearly 10% of Americans experience occasional difficulty sleeping. Stress support plays an important role in the management of occasional sleep problems. The Best-Sleep™ can be used to counteract the feelings of occasional nervousness that can inhibit sleep.

Symptoms of Stress, such as Mental Fatigue*
Serene Mind™ includes Sensoril® ashwagandha (Withania somnifera), rhodiola (Rhodiola rosea), and Panax ginseng, all of which are recognized adaptogens that promote a healthy response to both physical and mental stressors.* Sensoril ashwagandha is a multipatented and clinically tested herb that promotes emotional wellbeing, plus improves resistance to fatigue and tension caused by stress. Serene Mind™ also includes Sunphenon® green tea extract (Camellia sinensis), which supports mental focus and stamina. In addition, it contains the antioxidant choline bitartrate that promotes healthy liver function and increases acetylcholine synthesis to counteract the negative effects of stress. Stress has been linked to challenges in good health and well-being. A natural supplement, such as Serene Mind™ temporarily relieves the symptoms of stress, which can play an important role in the maintenance of good overall health.

Healthy Mood Balance*
Mental Sunshine™ is a natural supplement that helps promote healthy mood balance. This formula combines vitamin B6, inositol, saffron extract (Crocus sativus), and 5-HTP from Griffonia simplicifolia to encourage the production of brainsignaling molecules that support healthy mood balance. Occasional low levels of the neurotransmitter serotonin can impact our mood and the ability to cope with stress. Mental Sunshine™ provides the building blocks needed to assist the body in generating serotonin. The body requires vitamin B6 for the biosynthesis of serotonin; inositol is a core component of cell membrane phospholipids and serves as the foundation for serotonin; and saffron extract has a positive impact on serotonin metabolism. 5-HTP not only serves as a building block for serotonin, but also increases levels of endorphins. Supplementing with 5-HTP has been shown to promote feelings of well-being and improve sleep quality. Healthy students and adults whose hectic or stressful schedules are impacting their mood, behavior, or sleep quality will find Mental Sunshine™ to be a safe and effective supplement.

Natural Factors® Three Brains™ can help balance your heart, brain, and gut to promote optimal mental, emotional, and physical health. These supplements work synergistically to maintain the critical connection between our "three brains" by supporting brain and cognitive function, as well as cardiovascular and intestinal/ gastrointestinal health. They can be taken individually if you are looking for specific, targeted support or together if you need a more comprehensive approach. Natural Factors' great products take the guesswork out of supporting your three brains' health and have a positive impact on mental health and cognition!

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.


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